Donor heart for transplantation Total Artificial Heart -1981 HeartMate Ventricular Pump

1962 Texas Heart Institute founded by Denton A. Cooley, MD.

1968 First successful heart transplantation in the United States.

1969 First implantation in the world of an artificial heart in a human.

1974 Clayton Research Cardiac Catheterization Labs open.

1975 First study funded by the National Heart, Lung, and Blood Institute of an implantable left ventricular assist device (LVAD) for post-cardiotomy support.

1976 First accredited School of Perfusion Technology in the United States.

1977 Electrophysiology Lab opens on second floor.

1978 First bridge-to-transplant with an LVAD.

1981 Second implantation in the world of an artificial heart in a human.

1985

• First laser angioplasty procedure performed in the United States.
• First laser coronary endartectomy procedure performed in the United States.

1986

• First peripheral laser procedure in Texas, one of first in United States.
• First implant of the HeartMate pneumatically powered LVAD, as a bridge to transplant.

1990 First cases of MAZE surgery performed at St. Luke's Episcopal Hospital for atrial fibrillation.

1991 First patient in the world left the hospital with an electric, portable, battery-powered LVAD.

1993

• Selected as one of 7 centers in the United States to participate in the federal government's Heart Demonstration Project for Medicare patients.
• American Heart Association journal Circulation placed at THI/SLEH for an 11-year period, longer than any placement in its history.

1994 FDA approval to use the HeartMate pneumatic LVAD as a bridge to transplantation.

1996 FDA approval to use the electric HeartMate as a bridge to transplantation.

1998

• One of 6 centers chosen for cardiac magnetic resonance imaging trials.
• Groundbreaking for the new Texas Heart Institute at St. Luke's Episcopal Hospital—The Denton A. Cooley Building.

1999 FDA approval of a stent graft tested exclusively at THI/SLEH for repair of abdominal aortic aneurysms.

2000 First site for clinical trials of the Jarvik 2000, a miniature, axial flow left ventricular assist device.

2001

• First demonstration that C-Reactive Protein (CRP) causes vascular inflammation.
• 100,000th open heart operation performed.
• Completed REMATCH study, which compared long-term implantation of the HeartMate electric LVAD to conventional medical therapy for heart failure.
• Implantation of the AbioCor total artificial heart.

2002

• Dedication of the Texas Heart Institute at St. Luke's Episcopal Hospital–The Denton A. Cooley Building.
• HeartMate electric LVAD approved for destination therapy.

2003

• First nationally ranked cardiovascular center in the United States to open a cath lab medical simulation training center.
• First implantation of a HeartMate II LVAD in the United States.

2004

• First FDA-approved clinical trial of adult stem cell therapy for congestive heart failure in the United States.
• First U.S. patient to receive HeartMate II LVAD surpasses one year of survival with the device.

2006 1,000th heart transplant performed.

2007 National Institutes of Health selects THI as one of five centers for Stem Cell Study Consortium.