Surgical researchers at the Texas Heart Institute at St. Luke's Episcopal Hospital have reached many milestones over the years, including

• First implantation of a total artificial heart.
• Implantation of the first government-sponsored left ventricular assist device.
• First implantation of the Hemopump, a heart assist device the size of a pencil eraser.
• Implantation of the first electrical left ventricular assist device.
• First implantation of the Jarvik 2000 continuous flow assist device.
• Use of a laser to bore channels through the heart muscle to increase blood flow.
• Development and testing of a revolutionary new 3-leaflet mechanical heart valve.
• First implantation in the United States of the HeartMate II, designed for small adults and children.

Cardiology researchers at the Texas Heart Institute have made discoveries that improve patients’ lives in many ways. For example, they

• Discovered that warmer plaque is more likely to rupture and increase the risk of heart attack and sudden cardiac death.
• Used gene therapy to protect arteries from blood clots and from re-narrowing after a catheter interventional procedure.
• Developed special cells to line the inside of a heart assist device to protect the blood as it travels through the device.
• Designed new ways to place genes into cells.
• Tested a new gamma-radiation treatment intended to prevent arteries with stents from re-narrowing.
• Developed ways to see inside cells to learn how a disease progresses.
• Learned how vascular muscle cells communicate to produce substances that can help or hurt the heart.
• Found that elevated levels of a substance in the blood called C-reactive protein is not only a sign of heart disease but also a predictor of heart attack.

The Research section of this website provides more detail.

Updated March 2008