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View a video about stem cell research at Texas Heart Institute.
View a video about stem cell research at Texas Heart Institute.

 

 Emerson C. Perin, MD, PhD
View a video
in which
Dr. Emerson Perin discusses progress in world-leading adult stem cell studies.

Our Publications

Publications and Presentations

The following is a list of our recent scientific publications in the area of stem cell therapy. Abstracts of many of the following articles can be found at the National Institutes of Health free digital archive of biomedical and life sciences journal literature PubMed Central.

Patient Receives Allogeneic Mesenchymal Precursor Cells to Treat AMI
Perin, EC. Heart Watch 2008 Summer;2.

Predictors of Carotid Stent Restnosis
Younis GA, Gupta K, Mortazavi A, Strickman NE, Krajcer Z, Perin EC, Achari A. Catheterization and Cardiovascular Interventions 2007;69:673-682.

Stem cell therapy in end-stage ischemic heart failure: a catheter-based therapeutic strategy targeting myocardial viability.
Perin EC, Silva GV. EHJ Suppl 2007;Vol.8:H46-H51.

Remote-Controlled Magnetic Catheter Promises to Improve Delivery of Therapeutic Stem Cells to Damaged Myocardium
Perin EC. Heart Watch. 2007 Spring;1.

Stem cell therapy for cardiovascular disease
Perin, EC.Tex Heart Inst. J. 2006;33(2):204-8.

An Essential Guide to Cardiac Cell Therapy
Perin EC, Silva GV, and Willerson JT, eds. Informa 2006.

Hyperexpansion of coronary stents and clinical outcomes
de Quadros AS, Sarmento-Leite R, Gottschall CA,  Silva GV, Perin EC.
Tex Heart Inst. J. 2006;33(4):437-44.

Methods of stem cell delivery in cardiac diseases
Perin, EC, Lopez J. Nat Clin Pract Cardiovasc Med. 2006 Mar3;Suppl 1:S110-3.

New Clinical Trial Evaluates Promising Stem Cell Therapy for Peripheral Vascular Disease (PDF)
Perin EC. Heart Watch. 2006 Fall;4.

Stem cell delivery modalities (Chapter)
Silva G, Perin EC, Heinl-Green AC, Clague J, Alton EW.
In: An Essential Guide to Cardiac Cell Therapy
Perin EC, Silva GV and Willerson JR, eds. Informa 2006.

What are stem cells and what do they do? (Chapter)
Silva G, Perin EC.
In: An Essential Guide to Cardiac Cell Therapy
Perin EC, Silva GV, and Willerson JR, eds., Informa 2006

First Clinical Trial Will Evaluate New Stem Cell Technology for Heart Failure Therapy (PDF)
Perin EC. Heart Watch. 2006 Spring;1.

Intracoronary Infusion of Mesenchymal Stem Cells is Associated with Decreased Coronary Flow and Myocardial Injury in Dogs with Normal Coronaries
Silva GV, Souosa AL, Asad JA, Olivera E, Angeli F, Lopez J, Jimenez-Quevedo P, Willerson JT, Perin EC.  Circulation 2005;112(17):II-120.

Texas Heart Institute Establishes Center to Coordinate Stem Cell Research (PDF)
Willerson JT, Perin EC. Heart Watch. 2005 Spring;5.

The use of stem cell therapy for cardiovascular disease
Perin EC. Tex Heart Inst J. 2005;32(3):390-2.

Blood-derived progenitor cells after recanalization of chronic coronary artery occlusions in humans
Willerson JT, Yeh ET, Geng YJ, Perin EC. Circ Res. 2005 Oct 14;97(8):735-6.

Transendocardial autologous bone marrow mononuclear cell injection in ischemic heart failure: postmortem anatomicopathologic and immunohistochemical findings
Dohmann HF, Perin EC, Takiya CM, Silva GV, Silva SA, Sousa AL, Mesquita CT, Rossi MI, Pascarelli BM, Assis IM, Dutra HS, Assad JA, Castello-Branco RV, Drummond C, Dohmann HJ, Willerson JT, Borojevic R. Circulation. 2005 Jul 26;112(4):521-6.

Mesenchymal stem cells differentiate into an endothelial phenotype, enhance vascular density, and improve heart function in a canine chronic ischemia model
Silva GV, Litovsky S, Assad JA, Sousa AL, Martin BJ, Vela D, Coulter SC, Lin J, Ober J, Vaughn WK, Branco RV, Oliveira EM, He R, Geng YJ, Willerson JT, Perin EC. Circulation. 2005 Jan 18;111(2):150-6.

Stem cell therapy for cardiac diseases
Perin EC, Silva GV. Curr Opin Hematol. 2004 Nov;11(6):399-403.

Improved exercise capacity and ischemia 6 and 12 months after transendocardial injection of autologous bone marrow mononuclear cells for ischemic cardiomyopathy
Perin EC, Dohmann HF, Borojevic R, Silva SA, Sousa AL, Silva GV, Mesquita CT, Belem L, Vaughn WK, Rangel FO, Assad JA, Carvalho AC, Branco RV, Rossi MI, Dohmann HJ, Willerson JT. Circulation. 2004 Sep 14;110(11 Suppl 1):II213-8.

Catheter–Based Transendocardial Delivery of Autologous Bone-Marrow-Derived Mononuclear Cells in Patients Listed for Heart Transplantation
Silva GV, Perin EC, Dohmann HF, Borojevic R, Silva SA, Sousa AL, Assad JA, Vaughn WK, Mesquita CT, Belém L, Carvalho AC, Dohmann HJ, do Amaral EB, Coutinho J, Branco R, Oliveira E, Willerson JT. Tex Heart Inst J. 2004; 31(3): 214-219.

Transendocardial, autologous bone marrow cell transplantation for severe, chronic ischemic heart failure
Perin EC, Dohmann HF, Borojevic R, Silva SA, Sousa AL, Mesquita CT, Rossi MI, Carvalho AC, Dutra HS, Dohmann HJ, Silva GV, Belem L, Vivacqua R, Rangel FO, Esporcatte R, Geng YJ, Vaughn WK, Assad JA, Mesquita ET, Willerson JT. Circulation. 2003 May 13;107(18):2294-302.

Adult stem cell therapy in perspective
Perin EC, Geng YJ, Willerson JT. Circulation. 2003 Feb 25;107(7):935-8.

Comparison of Left Ventricular Electromechanical Mapping and Left Ventricular Angiography: Defining Practical Standards for Analysis of NOGA™ Maps
Sarmento-Leite R, Silva GV, Dohman HF, Rocha RM, Dohman HJ, de Mattos ND, Carvalho LA, Gottschall CA, Perin EC. Tex Heart Inst J. 2003; 30(1): 19-26.

Assessing myocardial viability and infarct transmurality with left ventricular electromechanical mapping in patients with stable coronary artery disease: validation by delayed-enhancement magnetic resonance imaging
Perin EC, Silva GV, Sarmento-Leite R, Sousa AL, Howell M, Muthupillai R, Lambert B, Vaughn WK, Flamm SD.Circulation. 2002 Aug 20;106(8):957-61.

Myocardial Revascularization – Novel Percutaneous Approaches (Chapter)
In: Left Ventricular Electromechanical Mapping As a Diagnostic Method
Perin EC, Silva GV, Leite RS. Edited by George S. Abela. Wiley-Liss 2002

Left Ventricular Electromechanical Mapping: A Case Study of Functional Assessment in Coronary Intervention
Perin EC, Silva GV, Sarmento-Leite R. Tex Heart Inst J. 2000; 27(3): 253-256.

Presentations

Stem Cell Therapy in Cardiovascular Disease  presented by Dr. Emerson C. Perin in March 2008 for Clinical Update 2008.

Stem Cell Therapy in Cardiovascular Disease presented by Dr. Emerson C. Perin in July 2007 at 7th Texas Update in Cardiovascular Advancements symposium.

Future Horizons: Stem Cell Therapy presented by Dr. Emerson C. Perin in November 2006 at Acute and Long-term Treatment of Cardiovascular Disease: Bringing Science to the Bedside symposium.

Bone Marrow Transplantation for Chronic Ischemic Cardiomyopathy presented by Dr. Emerson C. Perin in February 2006 at the Inaugural Conference of the International Society for Genomics, Proteomics and Cellular Therapy.

News and Publications About Our Research

Publications about our research by the press and other web resources.

Updated August 2008

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