Mission Statement
The Department of CV Anesthesiology is pursuing research designed to improve anesthesia and surgical care in patients with cardiovascular disease by exploring new methods to decrease mortality, morbidity, length of stay, and discomfort. Areas of interest include:
- Organ protection during cardiovascular surgery.
- The influence of genotype on perioperative risk and outcome.
- Gender-related outcomes after cardiovascular surgery.
- Methods to test coagulation and minimize blood loss following cardiovascular surgery.
- Influence of statins on perioperative outcomes.
- Novel drugs for the treatment of pain after cardiovascular surgery.
- Physiology of heart failure.
- Anesthetic management of patients with severe heart failure, particularly those requiring implantation of ventricular assist devices such as the JarvikTM LVAD, the AbiocorTM Total Artificial Heart, and other experimental devices.
Department Staff
C. David Collard, MD
Director, Cardiovascular Anesthesiology Research
Attending Physicians and CV Anesthesia Fellows
Research Nurses and Other Personnel
Cardiovascular Anesthesiology Department Homepage
Recent Staff Publications Hindler K, Cleeland CS, Rivera E, Collard CD. Role of statins in cancer therapy. Oncologist 2006;11:306-315.
Vrtovec B, Yazdanbakhsh AP, Pintar T, Collard CD, Gregoric I, Radovancevic B. QTc interval prolongation predicts post-operative mortality in heart failure patients undergoing surgical revascularization. Texas Heart Institute J. 2006;33:3-8.
Pan W, Hindler K, Lee V, Vaughn WK, Collard CD. Obesity in diabetic patients undergoing coronary artery bypass graft surgery is associated with increased postoperative morbidity. Anesthesiology 2006;104:441-447.
Hindler K, Eltzschig H, Collard CD. Influence of statins on perioperative outcomes. J. Cardiothorac. Vasc. Anesth. 2006;20:251-258.
Collard CD, Body SC, Shernan SK, Wang S, Mangano DT for the Multicenter Study of Perioperative Ischemia Research Group (McSPI); Ischemia Research and Education Foundation (IREF) Investigators. Preoperative statin therapy is associated with reduced cardiac mortality following coronary artery bypass graft surgery. J. Thorac. Cardiovasc. Surg. 2006;132(2):392-400.
Hindler K, Shaw AD, Samuels J, Fulton S, Collard CD, Riedel B. Reduction in postoperative morbidity and mortality by preoperative statin therapy: A systematic literature review and meta-Analysis. Anesthesiology 2006;Dec;105(6):1260-1272.
Bracey AW, Grigore AM, Nussmeier NA. Impact of Platelet Testing on Presurgical Screening and Implications for Cardiac and Noncardiac Surgical Procedures. Am J Cardiol. 2006 Nov 20;98(10S1):S25-S32
Sethi M, Grigore AM, Davison JK. Pro: It is safe to proceed with thoracoabdominal aortic aneurysm surgery after encountering a bloody tap during cerebrospinal fluid catheter placement. J Cardiothorac Vasc Anesth. 2006;Apr;20(2):269-72.
Cooper JR Jr, Abrams J, Frazier OH, Radovancevic R, Radovancevic B, Bracey AW, Kindo MJ, Gregoric ID. Fatal pulmonary microthrombi during surgical therapy for end-stage heart failure: possible association with antifibrinolytic therapy. J Thorac Cardiovasc Surg. 2006 May;131(5):963-8.
Blanchard L, Collard CD. Non-antiarrhythmic agents for prevention of postoperative atrial fibrillation: Role of statins. Curr Opin Anaesthesiol. 2007 Feb;20(1):53-56.
Cooper JR, GieseckeNM. Anesthesia for Cardiovascular Operations in "Cardiovascular Medicine", Third Edition. Willerson JT, Cohn JN, Editors, Springer; 2007.
Cooper JR: Anesthetic Management. In: “Aortic Arch Surgery: Principles, Strategies and Outcomes” Coselli JS, LeMaire SA, Editors, Blackwell Publishing; 2007.
Cooper JR, GieseckeNM: Hemodilution and Priming Solutions. In: “Cardiopulmonary Bypass, Principles and Practices,” Third Edition, Gravlee GP, Davis R, Stammers A, Ungerlaider R, Editors. New York: Lippincott, Williams & Wilkins; 2007.
Lotlikar P, Cooper JR: Mechanical Problems during Cardiopulmonary Bypass. In: “Complications in Anesthesia”, Second Edition. Atlee JL, Editor, Saunders/Elsevier, Philadelphia; 2007.
Fox A, Cooper JR: Anesthetic Management for Thoracic Aneurysms and Dissections in “A Practical Approach to Cardiac Anesthesia,” Fourth Edition. Hensley F, Martin DE, Gravlee GP, Editors. New York: Lippincott, Williams & Wilkins; 2007.
Sethi M, Collard CD. Thoracic aortic surgery. In: Yao FS, editor. "Yao and Artusio's Anesthesiology: Problem-oriented patient management". 6th ed. New York: Lippincott, Williams & Wilkins; 2007.
Thomas Z, Collard CD. Cardiac transplantation. In: Hensley FA, Martin DE, editors. "A practical approach to cardiac anesthesia". 4th ed. Boston: Little, Brown & Company; 2007.
Collard CD. Perioperative Care in Cardiac Anesthesia and Surgery. Cheng DCH, Tirone DE, editors. New York: Lippincott, Williams & Wilkins; 2006 [Book review]. Anesthesiology 2007.
Collard CD. “A razor may be sharper than an ax, but it cannot cut wood” -Annang Proverb [Editorial]. Anesthesiology 2007.
Bennet-Guerrero E, Grocott HP, Levy JH, Stierer KA, Hogue CW, Cheung, AT, Newman MF, Carter AA, Rossignol DP, Collard CD. A phase II double-blind placebo-controlled ascending dose study of eritoran (e5564), a lipid a antagonist, in patients undergoing cardiac surgery with cardiopulmonary bypass. Anesthesia & Analgesia 2007.
Sethi M, Collard CD. Perioperative Statin Therapy: Are Formal Guidelines and Physician Education Needed? Anesth Analg. 2007; 104(6):1322-1324.
Walsh MC, Shaffer LA, Body SC, Shernan S, Fox AA, Collard CD, Taylor RP, Stahl GL. Fluorochrome linked immunoassay for a complete functional analysis of the mannose binding lectin complement pathway. J Immunol Method 2007; 323:147-159.
Collard CD, Shernan SK, Fox AA, Vaughn WK, Toralf B, Chanock SJ, Takahashi K, Ezekowitz AB, Body SC. The MBL2 "LYQA Secretor" haplotype is an independent predictor of postoperative myocardial infarction in whites undergoing coronary artery bypass graft surgery. Circulation 2007; 116:I106-I122.
Tung S, Collard CD, Pan W. Metabolic syndrome increases operative mortality in patients undergoing coronary artery bypass graft surgery. Future Lipidology. 2008; 3(1):27-29.
Collard CD, Anton JM, Cooper JR Jr, Giesecke M. Contributions of Anesthesiology to the Surgical Treatment of Cerebrovascular Disease: The Role of Arthur S. Keats, MD. Anesthesiology 2008 Apr;108(4):756-8.
Sethi M, Anton JM, Collard CD. Is there a surgical role for topical aprotinin? Anesthesiology 2008; 108(5):967.
Le Manach Y, Coriat P, Collard CD, Riedel B. Statin therapy within the perioperative period. Anesthesiology 2008 Jun;108(6):1141-6.
Fox AA, Shernan SK, Collard CD, Jarolim P, Body SC. Preoperative brain natriuretic peptide independently predicts post-coronary artery bypass graft surgery ventricular dysfunction. J. Thorac. Cardiovasc. Surg. 2008 Aug;136(2):452-61.
Sethi M, Collard CD, Fontes M. Thoracic aortic surgery. In: Yao FS, editor. Yao and Artusio's anesthesiology: Problem-oriented patient management. 6th ed. New York: Lippincott, Williams & Wilkins; 2008; pp. 252-270.
Thomas Z, Rother AL, Collard CD. Cardiac transplantation. In: Hensley FA, Martin DE, Gravlee GP, editors. A practical approach to cardiac anesthesia. 4th ed. New York: Lippincott, Williams & Wilkins; 2008; pp. 439-463.
Contact Information and Location
Cardiovascular Anesthesiology Research Department
Phone: 832-355-2666
FAX: 832-355-6500
Mailing Address:
MC 1-226 PO Box 20345
Houston, TX 77225-0345
Texas Heart Institute at St. Luke's Episcopal Hospital—the Denton A. Cooley Building is located at 6770 Bertner Avenue. The Institute is adjacent to 
