Agenda subject to change
Friday – May 12, 2023
7:30 am Registration and Breakfast
7:45 Welcome | Emerson Perin, MD, PhD
OPENING SESSION: Cardiovascular Regeneration and Repair: Needs and Hopes | Chairs: Emerson Perin, MD, PhD; Francisco Fernandez–Aviles, MD, PhD and Joseph G. Rogers, MD
8:00 Keynote: Fostering a Culture of Physician Innovation | William Cohn, MD
8:30 Quick Perspective on the State of the Field of Cell Therapy | Emerson Perin, MD, PhD
8:35 Rapid History & Future of Regenerative Medicine for the Heart | Francisco Fernandez-Aviles, MD, PhD
8:40 Panel Discussion
Special Lecture
9:10 Setting the Stage for Cell Therapy in HF | Joseph G. Rogers, MD
SESSION I: Picking Up Where We Left Off: Clinical Advances in Cell Therapy and Regenerative Medicine Over the Last 3 Years – Ongoing and Recently Completed Trials | Chairs: Ricardo Sanz-Ruiz, MD, PhD and Leslie Miller, MD
9:20 Dream-HF: Main Results | Emerson Perin, MD, PhD
9:30 MSC-HF 4 Years Later/ SCIENCE | Jens Kastrup, MD
9:40 DCM II Trial | Joshua Hare, MD
9:50 Panel Discussion
10:10 Myocyte Trial | Ricardo Sanz-Ruiz, MD, PhD
10:20 CD 34 and Microvascular Angina | Timothy Henry, MD
10:30 Cardi-AMP | Carl Pepine, MD
10:40 Embryonic Cells for HF | Joseph Wu, MD, PhD
10:50 Panel Discussion
SESSION II: Advances in Translational Regenerative Medicine | Chairs: Camila Hochman-Mendez, PhD and Timothy Henry, MD
11:10 Neonatal Heart Regeneration | Jay Zhang, MD, PhD
11:20 IV Cell Therapy for HF | Roberto Bolli, MD
11:30 IPS | Young-sup Yoon, MD, PhD
11:40 Panel Discussion
12:00 Lunch
SESSION III: New Perspectives | Chairs: Emerson Perin, MD, PhD and Roberto Bolli, MD
1:00 Inflammation in HFpEF: Circumstantial or Key? | Matthew Segar, MD
1:10 Cell Therapy in HFpEF | Bojan Vrtovec, MD, PhD
1:20 LVAD and MPC Therapy | Ken Borow, MD
1:30 CSC’s and Arrhythmogenic Scar | Angel Arenal, MD
1:40 Surgical Delivery of Embryonic Cells/Products | Philippe Menasche, MD, PhD
1:50 Panel Discussion
SESSION IV: Roundtable | Introduction and Moderator: Stefan Janssens, MD, PhD
2:20 3 Important Questions to Consider in Regenerative Medicine | Francisco Fernandez-Aviles, MD, PhD; Roberto Bolli, MD; Joshua Hare, MD; Tim Henry, MD; Jens Kastrup, MD; Philippe Menasche, MD, PhD and Emerson Perin, MD, PhD
SESSION V: Regenerative Medicine in Organizations | Chairs: Francisco Fernandez-Aviles, MD, PhD and Joshua Hare, MD
3:00 TACTICS and Beyond: The ESC WG on CR&RM | Ricardo Sanz-Ruiz, MD, PhD
3:10 BRAV3 Consortium | Ricardo Sanz-Ruiz, MD, PhD
3:20 Netherlands: State of Cell Therapy | Douwe Atsma, MD, PhD
3:30 Panel Discussion
3:50 Adjourn
6:00 pm Dinner at Wiess Energy Hall – Museum of Natural Sciences
Saturday – May 13, 2023
8:00 am Registration and Breakfast
SESSION VI: The Ongoing Dilemma of Intramyocardial Delivery | Chairs: Ricardo Sanz-Ruiz, MD, PhD and Jerome Roncalli, MD, PhD
8:30 The Story of NOGA and Delivery: Targeting Necessary? | Emerson Perin, MD, PhD
8:40 Is C-Cath a Viable Alternative? | Jozef Bartunek, MD, PhD
8:50 Live Case Demonstration: New Tenaya Catheter w/Mapping Co-Registration | Emerson Perin, MD, PhD
9:20 Panel Discussion
SESSION VIIA: Issues with The Tissues | Chairs: Stefan Janssens, MD, PhD; Philippe Menasche, MD, PhD and Jens Kastrup, MD
9:40 Ploidy and Myocardial Repair | Mark Sussman, PhD
9:50 MVO and Regeneration | Jerome Roncalli, MD, PhD
10:00 Adult Cardiac Stem/Progenitor Cells Revisited: The Baby and the Bathwater | Daniele Torella, MD, PhD
10:10 Tissue Engineering and Beyond | Wolfram H. Zimmermann, MD
SESSION VIIB: Repair Without Cells
10:20 Intravascularly Infused Biomaterials for Treating Myocardial Infarction | Karen Christman, PhD
10:30 Targeting Cell Senescence to Improve Cardiac Regeneration | Georgina Ellison-Hughes, PhD
10:40 Panel Discussion
SESSION VIII: Gene Therapy | Chairs: Jim Martin, MD, PhD and Joseph Wu, MD, PhD
11:00 Back to the Future – Driving Paracrine Function in Regenerative Therapy | Marc Penn, MD, PhD
11:10 VEGF in Refractory Angina | Emerson Perin, MD, PhD
11:20 Hippo Pathway Inhibition | James Martin, MD, PhD
11:30 Cardiac Reprogramming | Kathy Ivey, PhD
11:40 Panel Discussion
SESSION IX: Future Perspectives | Chairs: Emerson Perin, MD, PhD and Francisco Fernandez-Aviles, MD, PhD
12:00 Automation in Regenerative Medicine | Camila Hochman-Mendez, PhD
12:10 Futuristic Applications in Bio-Electrophysiology | Mehdi Razavi, MD
12:20 pm Adjourn | Emerson Perin, MD, PhD and Francisco Fernandez-Aviles, MD, PhD