Da-Zhi Wang, PhD
Professor of Internal Medicine and of Molecular Pharmacology and Physiology in the College of Medicine at the University of South Florida
Director of the Center for Regenerative Medicine at USF
Director of the USF Heart Institute
Da-Zhi Wang, PhD
Prof. & Director Heart Inst., College of Medicine Internal Medicine
Professor, College of Medicine Molecular Pharmacology & Physiology
Dr. DaZhi Wang received his BS from Sichuan University and his MS from Peking University in China. He received his PhD from the University of Iowa in the laboratory of Prof. Jim Lin, where he studied molecular mechanisms of vertebrate development. Dr. Wang conducted his postdoctoral training with Prof. Eric Olson at the University of Texas Southwestern Medical Center studying heart development and disease. Dr. DaZhi Wang started his independent faculty position at The University of North Carolina at Chapel Hill and was promoted to Associate Professor with tenure there. Dr. Wang was recruited to the Department of Cardiology of Boston Children’s Hospital in 2009 and was promoted a tenured professor at Harvard Medical School in 2017. In 2021, Dr. Wang became the inaugural director of Center for Regenerative Medicine, USF Health Heart Institute and a Professor and Endowed Chair in Cardiovascular Research at University of South Florida.
Dr. Wang has dedicated his research career to the study of the molecular mechanisms that regulate mammalian development, cell fate determination, and human disease. He has made important contributions to understanding the fundamental processes regulating myocardial growth. Dr. Wang discovered the myocardin family of transcriptions factors and demonstrated their role in the cardiovascular system. In the past two decades, Dr. Wang increasingly focused on non-coding RNA’s, including microRNAs and long non-coding RNAs (lncRNAs), to understand how they regulate gene expression in the normal and diseased heart; in fact, Dr. Wang was among the first to recognize the importance of miRNAs in the regulation of muscle gene expression. His studies have resulted in over 100 publications in well-respected journals including Nature, Nature Medicine, Nature Genetics, Cell and PNAS. Dr. Wang is a recognized world leader in the study of heart development, cardiac function, and cardiovascular disease.
Dr. Wang was awarded the American Heart Association (AHA) Established Investigator award and was elected Fellow of American Heart Association (FAHA). He serves on the editorial board for many journals and has been an active reviewer for multiple funding agents, including the NIH and AHA. Dr. Wang has been invited to give more than 180n lectures and seminars worldwide. Dr. Wang’s investigation has been continuously supported by NIH. Dr. Wang has trained many young scientists, who now hold academic positions at well-established research institutions.
Overview:
- Demonstrate genetic evidence to support the function of miRNAs in the heart
- Critique basic molecular mechanism of how miRNAs work
- Define how miRNAs and RBPs could become novel therapies for disease
Objectives:
At the conclusion of the activity a participant should be able to:
- Knowledge of heart function and disease
- Potential of novel therapeutic targets and strategies for heart disease
- Animal models to study heart function and regeneration
Disclosures:
Da-Zhi Wang, PHD has nothing to disclose relevant to this program.
The Planning Committee has nothing to disclose relevant to this program.
The THI CME Staff has nothing to disclose relevant to this program.
The Program Reviewers has nothing to disclose relevant to this program.
Accreditation
Texas Heart Institute is accredited by the Accreditation Council for Continuing Medical Education (ACCME) to provide continuing medical education for physicians.
Credit Designation
Texas Heart Institute designates this live activity for a maximum of 1.00 AMA PRA Category 1 CreditsTM. Physicians should only claim credit commensurate with the extent of their participation in the activity.
Texas Heart Institute Grand Rounds is an esteemed tradition that attracts leading experts from around the world each year.
Series attendees include Cardiology Fellows and Faculty, members of the Departments of Internal Medicine and Cardiovascular Surgery, as well as visitors from other clinical and teaching institutions in the Texas Medical Center. We live broadcast Grand Rounds for online viewing on any desktop computer or mobile device.
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Obtain CME Credit
Accreditation and Credit Designation
Texas Heart Institute is accredited by the Accreditation Council or Continuing Medical Education (ACCME) to provide continuing medical education for physicians.
Texas Heart Institute designates this live activity for a maximum of 1.0 AMA PRA Category 1 CreditsTM. Physicians should claim only the credit commensurate with the extent of their participation in the activity.
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Questions? Contact CME@texasheart.org
