Frederick A. Meece
Texas Heart Institute Positions
- Senior Research Scientist, Molecular Cardiology Research
Publications
El Arba, M., Dibrell, S. E., Meece, F. et al. (2018). Ru(II)-catalyzed synthesis of substituted furans and their conversion to butenolides. Org Lett 20, 5886–5888. https://doi.org/10.1021/acs.orglett.8b02554.
Meece, F. A., Ahmed, G., Nair, H. et al. (2018). Esters of levonorgestrel and etonogestrel intended as single, subcutaneous-injection, long-lasting contraceptives. Steroids 137, 47–56. https://doi.org/10.1016/j.steroids.2018.07.010.
Widen, J. C., Kempema, A. M., Baur, J. W. et al. (2018). Helenalin analogues targeting NF-κB p65: thiol reactivity and cellular potency studies of varied electrophiles. ChemMedChem 13, 303–311. https://doi.org/10.1002/cmdc.201700752.
Ahmed, G., Elger, W., Meece, F. et al. (2017). A prodrug design for improved oral absorption and reduced hepatic interaction. Bioorg Med Chem 25, 5569–5575. https://doi.org/10.1016/j.bmc.2017.08.027.
Elger, W., Wyrwa, R., Ahmed, G. et al. (2017). Estradiol prodrugs (EP) for efficient oral estrogen treatment and abolished effects on estrogen modulated liver functions. J Steroid Biochem Mol Biol 165, 305–311. https://doi.org/10.1016/j.jsbmb.2016.07.008.
Kempema, A. M., Widen, J. C., Hexum, J. K. et al. (2015). Synthesis and antileukemic activities of C1-C10-modified parthenolide analogues. Bioorg Med Chem 23, 4737–4745. https://doi.org/10.1016/j.bmc.2015.05.037.
Alliband, A., Meece, F. A., Jayasinghe, C. et al. (2013). Synthesis and characterization of picket porphyrin receptors that bind phosphatidylglycerol, an anionic phospholipid found in bacterial membranes. J Org Chem 78, 356–362. https://doi.org/10.1021/jo302228w.
Burns, D. H., Meece, F. A., Moore, C. E. et al. (2009). Two similar dibenzo cyclic ethers with dissimilar conformations. Acta Crystallogr C 65, o27–o30. https://doi.org/10.1107/S0108270108040882.
Meece, F. A., Jayasinghe, C., Histand, G. et al. (2009). A convenient, one-step synthesis of benzyl (Ar) ureas of the type ArCH 2NHCONHR from Ar and R 1OCH 2NHCONHR via ureidoalkylation. J Org Chem 74, 3156–3159. https://doi.org/10.1021/jo900002n.
Siemer, C. J., Meece, F. A., Armstrong, W. H. et al. (2001). Iron, copper, and cobalt complexes of hydrotris(3-phenylpyrazolyl)borate and dihydrobis(3-phenylpyrazolyl)borate. Synthesis and X-ray crystallographic characterization. Polyhedron 20, 2637–2646. https://doi.org/10.1016/S0277-5387(01)00871-3.
