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Raja Muthupillai, PhD

Dr. Muthupillai is a biomedical imaging scientist with extensive experience in developing imaging methods to study tissue structure, function and metabolism. His pioneering work on MR elastography - an MRI based approach to measure tissue stiffness - has found numerous clinical applications. Show full bio

Dr. Muthupillai’s research interests include the development of rapid MR imaging methods to evaluate myocardial structure, function, and flow. He has published extensively and holds several patents. His current research focuses on developing approaches to reduce barriers to access for advanced imaging methods, typically restricted to tertiary-care settings, to the broader community.

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Current Projects

Education

  • Undergraduate:

    University of Madras

  • Postgraduate:

    Mayo Graduate School

Academic & Clinical Affiliations

Certifications

  • American Board of Radiology - Diplomate in Diagnostic Radiology
  • American Board of Medical Physics - Diplomate in Medical Physics (MRI)
  • American Board of MR Safety - MR Safety Expert (MRSE)

Honors, Awards and Memberships

Publications

Rajagopal, K. R., Myneni, M., Trevino, A. et al. (2023). Developing improved mathematical models of aortic mechanics. J Thorac Cardiovasc Surg, S0022-5223(23)00159–9. https://doi.org/10.1016/j.jtcvs.2023.02.004.
Kumar, P., Liu, C., Suliburk, J. et al. (2022). Supplementing glycine and n-acetylcysteine (glynac) in older adults improves glutathione deficiency, oxidative stress, mitochondrial dysfunction, inflammation, physical function, and aging hallmarks: A randomized clinical trial. J Gerontol A Biol Sci Med Sci, glac135. https://doi.org/10.1093/gerona/glac135.
Cheong, B. Y. C., Wilson, J. M., Preventza, O. A. et al. (2022). Gadolinium-based contrast agents: updates and answers to typical questions regarding gadolinium use. Tex Heart Inst J 49, e217680. https://doi.org/10.14503/THIJ-21-7680.
Pednekar, A. S., Cheong, B. Y. C. and Muthupillai, R. (2021). Ultrafast computation of left ventricular ejection fraction by using temporal intensity variation in cine cardiac magnetic resonance. Tex Heart Inst J 48, e207238. https://doi.org/10.14503/THIJ-20-7238.
Angelini, P., Muthupillai, R., Lopez, A. et al. (2021). Young athletes: Preventing sudden death by adopting a modern screening approach? A critical review and the opening of a debate. Int J Cardiol Heart Vasc 34, 100790. https://doi.org/10.1016/j.ijcha.2021.100790.
Cheong, B. Y. C., Wilson, J. M., Spann, S. J. et al. (2021). Coronary artery calcium scoring: an evidence-based guide for primary care physicians. J Intern Med 289, 309–324. https://doi.org/10.1111/joim.13176.
Kumar, P., Liu, C., Suliburk, J. W. et al. (2020). Supplementing Glycine and N-acetylcysteine (GlyNAC) in Aging HIV Patients Improves Oxidative Stress, Mitochondrial Dysfunction, Inflammation, Endothelial Dysfunction, Insulin Resistance, Genotoxicity, Strength, and Cognition: Results of an Open-Label Clinical Trial. Biomedicines 8, E390. https://doi.org/10.3390/biomedicines8100390.
Ajala, A., Zhang, J., Pednekar, A. et al. (2020). Mitral valve flow and myocardial motion assessed with dual-echo dual-velocity cardiac MRI. Radiol Cardiothorac Imaging 2, e190126. https://doi.org/10.1148/ryct.2020190126.
Angelini, P., Muthupillai, R., Cheong, B. et al. (2020). We have plenty of reasons to propose new, updated policies for preventing sudden cardiac death in young athletes. J Am Heart Assoc 9, e014368. https://doi.org/10.1161/JAHA.119.014368.
Duran, C., Masood, I., Duran, A. et al. (2020). Multidetector Computed Tomography (MDCT) angiography in the pre-procedural assessment of patients undergoing transcatheter aortic valve replacement. Eurasian J Med 52, 86–93. https://doi.org/10.5152/eurasianjmed.2019.18329.